PL EN DE RU UA
Nuclear Medicine

Calculator

(formerly accessible on: www.nuk.bieganski.org)

General math & medicine options

Arithmetic mean and standard deviation
Regression of points to straight line, correlation coefficient
Finding of natural divisors
The highest common divisor
Polynomials
Time difference
Estimation of some human biometric parameters
Concentration conversion
Pharmacokinetic compartment models

Calculations related to nuclear physics

Examples of application of the programs below are accessible here.
Simple radioactive decay (1 radioactive nuclide: A → B)
Successive radioactive decay (2 radioactive nuclides: A → B → C)
Successive radioactive decay (3 radioactive nuclides: A → B → C → D)
Conversion of activity units (traditional into SI-derived and vice versa)
Conversion of mass into activity and vice versa (mass-units into activity-units and vice versa)

Calculations related to nuclear medicine

Instruction for the programs below is accessible here.
(1.) Calculation of thyroid volumen on the basis of the lobes diameters
(2.) Calculation of (radio)nuclide uptake (f.e. uptake of radioiodine in the thyroid)
 (2a.) Calculation of uptake of I-131 in the thyroid (This program can be saved as a file and launched in another PC, a browser with HTML and JavaScript is necessary; in Polish).
(3.) Calculation of radioiodine dose (simplified)
(4.) Kinetic modeling I. (effective half-time, maximal uptake and others, based on a series of measures) - for radionuclide therapy
(5.) Kinetic modeling II. (effective half-time, maximal uptake and others, based on three measures) - for radionuclide therapy
(6.) Calculation of dose of radioiodine or another radionuclide for treatment (modified Marinelli-formula)
(7.) Dosimetry of α- and β-radiation
(8.) Dose rate and absorbed dose of γ radiation (in a distance from a point source)

Some human parameters

It calculates body mass index (BMI), estimates body surface area (BSA, formulas of DuBois, of Mosteller, and of Haycock), total body water (TBW, formulae of Watsons and of Hume; about 2/3 of this amount is cytoplasm, 1/3 - extracellular fluid), extracellular fluid (ECF, according to Abraham and to Bird), and circulating blood volume (CBV, formulae of Nadler): cell volume (CV) and plasma volume (PV) Optionally, glomerular filtration rate (GFR) according to the Cockroft-Gault formula is estimated.

Required data:
- W (weight) [kg],
- H (height) [cm],
- A (age) [y],
- G (gender): m (male) or f (female),
- HCT (hematocrite) [%],
- CRE (creatinin, optional) [mg/dl].

W[kg]
H[cm]
A[y]
G
HCT[%]
CRE[mg/dl]



©Author: Cyprian Świętaszczyk, 2013; last update: 07.2020